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Recent advances in asymmetric phosphine oxide catalysis

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Abstract Phosphine oxides are versatile catalysts in organic synthesis and mediate a broad range of transformations. In this digest, we reviewed the recent developments in phosphine oxide-catalyzed asymmetric reactions. The… Click to show full abstract

Abstract Phosphine oxides are versatile catalysts in organic synthesis and mediate a broad range of transformations. In this digest, we reviewed the recent developments in phosphine oxide-catalyzed asymmetric reactions. The enantioselective double aldol reactions, enantioselective aldol reaction of carboxylic acids, and enantioselective halocyclizations were discussed. These novel phosphine oxide-catalyzed processes are vital for the stereoselective synthesis and functionalization of useful organic molecules and intermediates.

Keywords: phosphine oxide; asymmetric phosphine; advances asymmetric; recent advances; oxide catalysis

Journal Title: Tetrahedron Letters
Year Published: 2020

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