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Abstract A novel and sustainable route for the synthesis of isoquinoline was developed by reacting 2-ethynylbenzaldehyde with ammonium hydroxide in water. This method provides a convenient, atom-economical, and catalyst-free access… Click to show full abstract
Abstract A novel and sustainable route for the synthesis of isoquinoline was developed by reacting 2-ethynylbenzaldehyde with ammonium hydroxide in water. This method provides a convenient, atom-economical, and catalyst-free access to diversely substituted isoquinolines with moderate to good yields.
Keywords:
additive free;
catalyst additive;
water;
free endo;
endo dig;
access
Journal Title: Tetrahedron Letters
Year Published: 2020
Link to full text (if available)
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Journal Title: Tetrahedron Letters
Year Published: 2020
Link to full text (if available)
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recommendations!