Abstract A stereodivergent approach to 2-alkynyl buta-1,3-dienes from a single stereoisomer of starting α-bromoenal has been developed. By simply switching the sequence of Sonogashira and Horner-Wadsworth-Emmons reactions, it is possible… Click to show full abstract
Abstract A stereodivergent approach to 2-alkynyl buta-1,3-dienes from a single stereoisomer of starting α-bromoenal has been developed. By simply switching the sequence of Sonogashira and Horner-Wadsworth-Emmons reactions, it is possible to obtain these branched dienynes with retention or almost complete inversion of the double bond configuration.
Keywords:
alkynyl buta;
retention;
geometry;
buta dienes
Journal Title: Tetrahedron Letters
Year Published: 2020
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Journal Title: Tetrahedron Letters
Year Published: 2020
Link to full text (if available)
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recommendations!