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Abstract An atom-economic approach to synthesize 1,2,4-trisubstituted pyrroles through palladium-catalyzed imine-directed intramolecular C(sp3) H amination reaction has been developed. The imine group acts as a directing group as well as… Click to show full abstract
Abstract An atom-economic approach to synthesize 1,2,4-trisubstituted pyrroles through palladium-catalyzed imine-directed intramolecular C(sp3) H amination reaction has been developed. The imine group acts as a directing group as well as an intramolecular nucleophile for the first time in intramolecular C N bonds formation reactions.
Keywords:
sp3;
imine directed;
approach;
directed intramolecular;
catalyzed imine
Journal Title: Tetrahedron Letters
Year Published: 2020
Link to full text (if available)
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Journal Title: Tetrahedron Letters
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!