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Abstract Trisubstituted allenamides are synthesized by the isomerization of propargylamides with DBU. The reactions afforded a variety of substituted allenamides under simple and mild conditions. One-pot synthesis of allenamides from… Click to show full abstract
Abstract Trisubstituted allenamides are synthesized by the isomerization of propargylamides with DBU. The reactions afforded a variety of substituted allenamides under simple and mild conditions. One-pot synthesis of allenamides from propargylamines, which were easily prepared by aldehyde-alkyne-amine coupling in one-step, is also achieved.
Keywords:
facile synthesis;
isomerization propargylamides;
trisubstituted allenamides;
synthesis trisubstituted
Journal Title: Tetrahedron Letters
Year Published: 2020
Link to full text (if available)
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Journal Title: Tetrahedron Letters
Year Published: 2020
Link to full text (if available)
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recommendations!