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FeCl3-catalyzed sequential cyclization for the construction of 12-aryl 5,7-dihydropyrido[2,3-b:6,5-b']diindoles

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Abstract A facile approach to prepare 12-aryl 5,7-dihydropyrido[2,3-b:6,5-b']diindoles via tandem cyclizations is described. FeCl3 is used as the catalyst for the reaction between o-aminophenylacetonitriles and aromatic aldehydes, generating 5,7-dihydropyrido[2,3-b:6,5-b']diindoles derivatives… Click to show full abstract

Abstract A facile approach to prepare 12-aryl 5,7-dihydropyrido[2,3-b:6,5-b']diindoles via tandem cyclizations is described. FeCl3 is used as the catalyst for the reaction between o-aminophenylacetonitriles and aromatic aldehydes, generating 5,7-dihydropyrido[2,3-b:6,5-b']diindoles derivatives in moderate to high yields.

Keywords: fecl3 catalyzed; dihydropyrido diindoles; dihydropyrido; sequential cyclization; aryl dihydropyrido; catalyzed sequential

Journal Title: Tetrahedron Letters
Year Published: 2020

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