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Abstract A copper(II)-catalyzed oxidative reaction for the one-pot simultaneous synthesis of quinolines and gem-diamine derivatives from N-arylglycine ethyl esters and enamides is described. In this reaction, the two fragments in… Click to show full abstract
Abstract A copper(II)-catalyzed oxidative reaction for the one-pot simultaneous synthesis of quinolines and gem-diamine derivatives from N-arylglycine ethyl esters and enamides is described. In this reaction, the two fragments in an enamide substrate react with the same intermediate generated in situ from an N-arylglycine ethyl ester, respectively, producing two products simultaneously. This reaction has the advantages of high efficiency, simple operation and high atom economy.
Keywords:
quinolines gem;
pot simultaneous;
gem diamine;
simultaneous synthesis;
one pot;
synthesis quinolines
Journal Title: Tetrahedron Letters
Year Published: 2020
Link to full text (if available)
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Journal Title: Tetrahedron Letters
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!