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The coupling reaction of α-silylamines with Baylis-Hillman adducts by visible light photoredox catalysis

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Abstract The preparation of N-containing α,β-unsaturated carboxylate derivatives from α-silylamine and Baylis-Hillman adducts under visible light irradiation was reported. The formation of α-aminoalkyl radical is regioselective compared with the previous… Click to show full abstract

Abstract The preparation of N-containing α,β-unsaturated carboxylate derivatives from α-silylamine and Baylis-Hillman adducts under visible light irradiation was reported. The formation of α-aminoalkyl radical is regioselective compared with the previous reports. The reaction was successfully performed without additional additives under mild conditions.

Keywords: adducts visible; baylis hillman; visible light; coupling reaction; hillman adducts

Journal Title: Tetrahedron Letters
Year Published: 2021

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