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Abstract An efficient catalytic enantioselective 1,4-addition reaction of 3-substituted indoles, pyrroles and furans with substitution of azadienes by a chrial phosphoric acid was developed. A large variety of C2 substituted… Click to show full abstract
Abstract An efficient catalytic enantioselective 1,4-addition reaction of 3-substituted indoles, pyrroles and furans with substitution of azadienes by a chrial phosphoric acid was developed. A large variety of C2 substituted triarylmethanes derivatives were achieved in moderate to good yields (up to 98 %) with generally excellent enantioselectivities (up to 99 % ee).
Keywords:
substituted indoles;
phosphoric acid;
addition;
enantioselective synthesis;
synthesis hetero
Journal Title: Tetrahedron Letters
Year Published: 2021
Link to full text (if available)
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Journal Title: Tetrahedron Letters
Year Published: 2021
Link to full text (if available)
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recommendations!