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Abstract A base/DMAP system for efficient oxidative cleavage of C(CO)–C(alkyl) bond to generate N-substituted benzamides has been developed in the presence of copper(I) chloride. The usage of inexpensive copper catalyst,… Click to show full abstract
Abstract A base/DMAP system for efficient oxidative cleavage of C(CO)–C(alkyl) bond to generate N-substituted benzamides has been developed in the presence of copper(I) chloride. The usage of inexpensive copper catalyst, broad substrate scope, mild conditions make this protocol very practical. More importantly, this reaction provides an alternative approach for the construction of useful N-substituted benzamides.
Keywords:
substituted benzamides;
cleavage;
copper catalysed;
dmap;
bond
Journal Title: Tetrahedron Letters
Year Published: 2021
Link to full text (if available)
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Journal Title: Tetrahedron Letters
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!