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Immune Responses - Transcriptional and Post-Transcriptional Networks Pass the Baton.

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Diverse gene regulatory mechanisms impact on immune homeostasis, and a new model now emerges as fundamental in light of recent genome-wide studies. In this picture, transcriptional networks drive functional changes… Click to show full abstract

Diverse gene regulatory mechanisms impact on immune homeostasis, and a new model now emerges as fundamental in light of recent genome-wide studies. In this picture, transcriptional networks drive functional changes during immune activation, whereas autoregulatory feedback loops of post-transcriptional programs ensure the original cell lineage identity and subsequent immune resolution.

Keywords: post transcriptional; immune responses; transcriptional post; transcriptional networks; responses transcriptional; networks pass

Journal Title: Trends in biochemical sciences
Year Published: 2018

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