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Nonclassical class I MHC-like molecules are ligands for several unconventional T cell populations. Recently, Le Nours et al. identified human γδ T cells recognising MHC-related protein-1 (MR1) via their T… Click to show full abstract
Nonclassical class I MHC-like molecules are ligands for several unconventional T cell populations. Recently, Le Nours et al. identified human γδ T cells recognising MHC-related protein-1 (MR1) via their T cell receptor (TCR). Also recognised by the αβ-TCR of mucosal associated invariant T cells, MR1 interacts with specific γδ-TCRs using strikingly diverse binding modes, suggesting fundamental differences in γδ T cell recognition.
Keywords:
recognition mr1;
mr1 adapting;
tcr recognition;
adapting life;
mr1;
recognition
Journal Title: Trends in Biochemical Sciences
Year Published: 2020
Link to full text (if available)
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Journal Title: Trends in Biochemical Sciences
Year Published: 2020
Link to full text (if available)
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recommendations!