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In a recent study, Hervas et al. extracted Orb2 fibrils, that are involved in long-term memory formation, from Drosophila brains, characterised their function, and determined their structure using cryo-electron microscopy… Click to show full abstract
In a recent study, Hervas et al. extracted Orb2 fibrils, that are involved in long-term memory formation, from Drosophila brains, characterised their function, and determined their structure using cryo-electron microscopy (cryo-EM). The fibrils show a remarkable resemblance to amyloid β (Aβ) fibrils associated with Alzheimer's disease, highlighting the subtle difference between functional and dysfunctional amyloid.
Keywords:
difference function;
amyloid fibrils;
amyloid;
spot difference
Journal Title: Trends in biochemical sciences
Year Published: 2020
Link to full text (if available)
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Journal Title: Trends in biochemical sciences
Year Published: 2020
Link to full text (if available)
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recommendations!