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Minicircle DNA (mcDNA) is a smaller and safer version of non-viral DNA vectors that results from a cutting-edge in vivo recombination process to excise prokaryotic sequences from plasmid DNA (pDNA).… Click to show full abstract
Minicircle DNA (mcDNA) is a smaller and safer version of non-viral DNA vectors that results from a cutting-edge in vivo recombination process to excise prokaryotic sequences from plasmid DNA (pDNA). Considering the molecule's potential and increasing interest as a non-viral DNA-based therapeutic, biomanufacturing methodologies need to be improved, especially in downstream processing.
Keywords:
minicircle dna;
dna based;
dna;
based vectors;
future dna;
dna future
Journal Title: Trends in biotechnology
Year Published: 2020
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Journal Title: Trends in biotechnology
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!