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Reductive Glycine Pathway: A Versatile Route for One-Carbon Biotech.

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Hong et al. heterologously expressed the metabolic core of the reductive glycine pathway (rGlyP) as a sink for the anaerobic conversion of glycerol. This recent study concludes several reports in… Click to show full abstract

Hong et al. heterologously expressed the metabolic core of the reductive glycine pathway (rGlyP) as a sink for the anaerobic conversion of glycerol. This recent study concludes several reports in 2020 on the ATP-efficient, one-carbon-assimilating, rGlyP. Its engineering in diverse hosts could help the transformation toward renewable, one-carbon-based bioproduction.

Keywords: one carbon; glycine pathway; reductive glycine; carbon

Journal Title: Trends in biotechnology
Year Published: 2021

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