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For Viral Reservoir Studies, Timing Matters.

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New strategies to eliminate persistent HIV-1 during therapy will benefit from animal models, such as non-human primates infected with simian immunodeficiency viruses (SIV) or chimeras (SHIV). Understanding the genetic composition… Click to show full abstract

New strategies to eliminate persistent HIV-1 during therapy will benefit from animal models, such as non-human primates infected with simian immunodeficiency viruses (SIV) or chimeras (SHIV). Understanding the genetic composition of SIV and SHIV reservoirs during therapy is therefore crucial for the future application of this model.

Keywords: timing matters; studies timing; reservoir studies; viral reservoir

Journal Title: Trends in microbiology
Year Published: 2019

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