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Legionella pneumophila encodes a family of phosphoribosyl ubiquitination ligases (SidE) essential for the bacterium to establish successful infection. Four independent studies now show that the SidE family of ubiquitin ligases… Click to show full abstract
Legionella pneumophila encodes a family of phosphoribosyl ubiquitination ligases (SidE) essential for the bacterium to establish successful infection. Four independent studies now show that the SidE family of ubiquitin ligases are regulated by a novel mechanism of glutamylation via a pseudokinase-like Legionella effector, SidJ, in an ATP- and calmodulin-dependent manner.
Keywords:
ligases legionella;
bacterial ubiquitin;
ubiquitin ligases;
glutamylation bacterial;
pseudokinase;
glutamylation
Journal Title: Trends in microbiology
Year Published: 2019
Link to full text (if available)
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Journal Title: Trends in microbiology
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!