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Fungal pathogens represent a rising threat against immunocompromised patients. By using Aspergillus fumigatus, Briard et al. showed that the cell wall galactosaminogalactan (GAG) triggers macrophage inflammasome activation, promoting protective immunity.… Click to show full abstract
Fungal pathogens represent a rising threat against immunocompromised patients. By using Aspergillus fumigatus, Briard et al. showed that the cell wall galactosaminogalactan (GAG) triggers macrophage inflammasome activation, promoting protective immunity. This provides new insights into the role of GAG in host-pathogen interactions and also perspectives for developing GAG-based anti-inflammatory therapeutics.
Keywords:
promote protective;
immunity;
protective immunity;
fungal polysaccharides;
polysaccharides promote
Journal Title: Trends in microbiology
Year Published: 2021
Link to full text (if available)
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Journal Title: Trends in microbiology
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!