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Recently, Martelli and colleagues reported on the structural and functional characterization of new antimycobacterials based on N-thio-β-lactams. Surprisingly, the inhibitory mechanism follows a path unexpected for β-lactams, providing an alternative… Click to show full abstract
Recently, Martelli and colleagues reported on the structural and functional characterization of new antimycobacterials based on N-thio-β-lactams. Surprisingly, the inhibitory mechanism follows a path unexpected for β-lactams, providing an alternative route to defeat drug-resistant strains of Mycobacterium tuberculosis.
Keywords:
repurposing lactams;
dog new;
new tricks;
tricks repurposing;
teaching old;
old dog
Journal Title: Trends in pharmacological sciences
Year Published: 2021
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Journal Title: Trends in pharmacological sciences
Year Published: 2021
Link to full text (if available)
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recommendations!