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Solute carrier transporters (SLCs) limit receptor activation via uptake of extracellular ligands. Novel concepts are emerging that describe the modulation of intracellular and plasma membrane receptors by ligand influx and… Click to show full abstract
Solute carrier transporters (SLCs) limit receptor activation via uptake of extracellular ligands. Novel concepts are emerging that describe the modulation of intracellular and plasma membrane receptors by ligand influx and efflux via SLCs, respectively. Here, we evaluate recent insights and provide an outlook for developing potential therapeutic strategies.
Keywords:
carriers modulate;
solute;
modulate receptor;
receptor;
solute carriers;
targeting solute
Journal Title: Trends in pharmacological sciences
Year Published: 2022
Link to full text (if available)
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Journal Title: Trends in pharmacological sciences
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!