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Here we discuss the potential of targeting Dihydroorotate dehydrogenase enzyme to heltreat Covid 19 Next, we present a very large scale of docking analysis using 7900 drug candidates and 20… Click to show full abstract
Here we discuss the potential of targeting Dihydroorotate dehydrogenase enzyme to heltreat Covid 19 Next, we present a very large scale of docking analysis using 7900 drug candidates and 20 Dihydroorotate dehydrogenase structures Our findings not only identify 28-FDA approved candidate molecules, but also show common characteristics among the candidates, especially their association with serotonin-dopamine receptors In continuation, we discuss the existing clinical trials for Covid 19 treatment of some of the drug candidates we have identified, supporting that the rest are good candidates
Journal Title: Travel Medicine and Infectious Disease
Year Published: 2020
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