Highlights • We evaluated glyphosate, isoxaflutole, quizalofop-p-ethyl and mesotrione.• Gene expression alterations were measured in the HepaRG liver cell line.• Quizalofop-p-ethyl was the most toxic, causing alterations in lipid metabolism.•… Click to show full abstract
Highlights • We evaluated glyphosate, isoxaflutole, quizalofop-p-ethyl and mesotrione.• Gene expression alterations were measured in the HepaRG liver cell line.• Quizalofop-p-ethyl was the most toxic, causing alterations in lipid metabolism.• Isoxaflutole was less toxic, but was revealed as a possible PXR activator.• Glyphosate and mesotrione only caused subtle changes in transcriptome profiles.
               
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