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Genotoxicity and acute toxicity evaluation of the three amino acid additives with Corynebacterium glutamicum biomass

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Highlights • The three amino acid additives with C. glutamicum were found to be non-mutagenic and non-toxic.• Genotoxicity is not observed in Ames assay and mammalian cytogenentic assay of the… Click to show full abstract

Highlights • The three amino acid additives with C. glutamicum were found to be non-mutagenic and non-toxic.• Genotoxicity is not observed in Ames assay and mammalian cytogenentic assay of the three amino acid additives.• No clinical signs, mortalities, abnormal necropsy findings were observed in acute oral toxicity in both Sprague-Dawley and Wistar rats.

Keywords: amino acid; acid additives; genotoxicity; toxicity; three amino

Journal Title: Toxicology Reports
Year Published: 2020

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