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Highlights • Chronic intake of alcohol initiates a pathogenic process that involves the production of protein-aldehyde adducts, and release of cytokines.• Involved gene polymorphisms may include alcohol dehydrogenase, cytochrome P4502E1,… Click to show full abstract
Highlights • Chronic intake of alcohol initiates a pathogenic process that involves the production of protein-aldehyde adducts, and release of cytokines.• Involved gene polymorphisms may include alcohol dehydrogenase, cytochrome P4502E1, and those associated with alcoholism.• Alcohol ingestion could be correlated to the risk of preterm births, there is no exact dose-response relationship.• Oral drugs of pentoxifylline have reduced the severity of steatohepatitis in alcohol-use patients.
Journal Title: Toxicology Reports
Year Published: 2021
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