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Acute toxicity evaluation of a novel ceramide analog for the treatment of breast cancer

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Highlights • Novel ceramide drug for breast cancer.• Toxicological profile was studied.• Single dose of 80 mg/kg dose was safe.• Single dose of 120 mg/kg caused minor liver and cardiac… Click to show full abstract

Highlights • Novel ceramide drug for breast cancer.• Toxicological profile was studied.• Single dose of 80 mg/kg dose was safe.• Single dose of 120 mg/kg caused minor liver and cardiac tissue damage.

Keywords: acute toxicity; novel ceramide; toxicity evaluation; breast cancer

Journal Title: Toxicology Reports
Year Published: 2021

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