Although widely used as a marker for cell proliferation, CYCB1;1 expression is also strongly induced in cells that suffer from DNA damage. Recently, this enigmatic dual expression pattern has been… Click to show full abstract
Although widely used as a marker for cell proliferation, CYCB1;1 expression is also strongly induced in cells that suffer from DNA damage. Recently, this enigmatic dual expression pattern has been resolved by proving that CYCB1;1 promotes DNA repair. This has consequences for using CYCB1;1 as a cell cycle reporter.
               
Click one of the above tabs to view related content.