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Evaluation of 99mTc-CN5DG as a broad-spectrum SPECT probe for tumor imaging

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Highlights • 99mTc-CN5DG exhibited high tumor uptake, tumor/muscle and tumor/blood ratios in different kinds of tumor models.• 99mTc-CN5DG was stable in blood and tumors in vivo and rapidly cleared from… Click to show full abstract

Highlights • 99mTc-CN5DG exhibited high tumor uptake, tumor/muscle and tumor/blood ratios in different kinds of tumor models.• 99mTc-CN5DG was stable in blood and tumors in vivo and rapidly cleared from blood.• SPECT/CT images in four tumor models demonstrated that all four kinds of tumors could be clearly detected.

Keywords: evaluation 99mtc; tumor; spect; cn5dg broad; 99mtc cn5dg

Journal Title: Translational Oncology
Year Published: 2020

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