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Highlights • Approximately 650,000 people will be diagnosed this year with cancers of the oral cavity and pharynx worldwide.• The absence of biomarkers for the disease early detection contributes to… Click to show full abstract
Highlights • Approximately 650,000 people will be diagnosed this year with cancers of the oral cavity and pharynx worldwide.• The absence of biomarkers for the disease early detection contributes to the late diagnosis.• Despite some advances with regards to treatment, overall survival has not significantly improved in decades.• We have shown that increased relative mRNA expression of KLK5 to LEKTI is associated with disease’s poor outcome.• This work supports the relative expression of KLK5 to LEKTI as a valuable prognostic marker.
Journal Title: Translational Oncology
Year Published: 2020
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