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Highlights • CUP occurs in as many as 3–5% of patients when standard diagnostic tests are not able to determine the origin of cancer.• MI GPSai (Genomic Prevalence Score) is… Click to show full abstract
Highlights • CUP occurs in as many as 3–5% of patients when standard diagnostic tests are not able to determine the origin of cancer.• MI GPSai (Genomic Prevalence Score) is an AI that uses genomic and transcriptomic data to elucidate tumor origin.• The algorithm was trained on molecular data from 57,489 cases and validated on 19,555 cases.• MI GPSai predicted the tumor type out of 21 options in the labeled data set with an accuracy of over 94% on 93% of cases.• When also considering the second highest prediction, the accuracy increases to 97%.
Journal Title: Translational Oncology
Year Published: 2021
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