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Highlights • The cytotoxic protein PRF1 is essentially involved in anti-tumour immunity.• PRF1 is overexpressed in advanced HPV+ HNSCC and correlates with better OS.• PRF1 expression correlates with tumour infiltrating… Click to show full abstract
Highlights • The cytotoxic protein PRF1 is essentially involved in anti-tumour immunity.• PRF1 is overexpressed in advanced HPV+ HNSCC and correlates with better OS.• PRF1 expression correlates with tumour infiltrating CD8+ t cells and dendritic cells in HPV+ HNSCC.• PRF1 expression correlates with gene markers of t cell exhaustion in HNSCC.
Keywords:
correlated immune;
prf1 prognostic;
prognostic marker;
immune infiltration;
marker correlated;
prf1
Journal Title: Translational Oncology
Year Published: 2021
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Journal Title: Translational Oncology
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!