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Highlights • Tumor microenvironment (TME) was compared among multiple primary lung cancers (MPLCs).• Sex and smoking status concomitantly impacted PD-L1 expression in paired tumors.• EGFR mutations were independently associated with… Click to show full abstract
Highlights • Tumor microenvironment (TME) was compared among multiple primary lung cancers (MPLCs).• Sex and smoking status concomitantly impacted PD-L1 expression in paired tumors.• EGFR mutations were independently associated with PD-L1 expression.• KRAS mutations altered the TMEs according to the types of co-mutations.• The number of FOXP3-positive t cells reflected histological subtypes.
Keywords:
primary lung;
multiple primary;
histological subtypes;
tumor microenvironment;
lung cancers
Journal Title: Translational Oncology
Year Published: 2021
Link to full text (if available)
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Journal Title: Translational Oncology
Year Published: 2021
Link to full text (if available)
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recommendations!