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A novel tailored immune gene pairs signature for overall survival prediction in lower-grade gliomas

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Highlights • The Immune-related gene pairs (IRGPs) pronostic signature for LGG is correlated with immune cells infiltration.• WGCNA presented a gene set correlating with immune cells infiltration and genes co-expression… Click to show full abstract

Highlights • The Immune-related gene pairs (IRGPs) pronostic signature for LGG is correlated with immune cells infiltration.• WGCNA presented a gene set correlating with immune cells infiltration and genes co-expression relationships were visualized.• The nomogram constrcted by three IRGPs and clinical factors is a novel tailored tool for individual-level prediction.

Keywords: tailored immune; gene pairs; novel tailored; immune gene; gene; prediction

Journal Title: Translational Oncology
Year Published: 2021

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