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Highlights • Most patient with pancreatic cancer are treated by chemotherapy.• Treatments selection are not personalized on the tumor characteristics.• Signatures predicting chemotherapy efficiency are essential for personalizing treatments.• An… Click to show full abstract
Highlights • Most patient with pancreatic cancer are treated by chemotherapy.• Treatments selection are not personalized on the tumor characteristics.• Signatures predicting chemotherapy efficiency are essential for personalizing treatments.• An RNA signature of gemcitabine-sensitivity is developed leveraged on the dissimilarities between 2D and 3D in vitro models.• Combining different in vitro models can help in defining clinically efficient transcriptomic signatures.
Keywords:
relevance biopsy;
efficient transcriptomic;
transcriptomic signatures;
biopsy derived;
pancreatic cancer
Journal Title: Translational Oncology
Year Published: 2021
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Journal Title: Translational Oncology
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!