Photo by nci from unsplash
Highlights • The increased cancer incidence in patients with glomerular disease can be secondary to an intrinsic immune dysfunction associated with the disease or/and extrinsic factors, especially immunosuppressants.• Paraneoplastic glomerulopathy… Click to show full abstract
Highlights • The increased cancer incidence in patients with glomerular disease can be secondary to an intrinsic immune dysfunction associated with the disease or/and extrinsic factors, especially immunosuppressants.• Paraneoplastic glomerulopathy is sometimes misdiagnosed as primary glomerulopathy.• The treatment for paraneoplastic glomerulopathy is different from primary glomerular disease.• In membranous nephropathy, serum circulating autoantibodies against PLA2R and THSD7A, immunohistochemical tissue markers for glomerular PLA2R, THSD7A and specific types of immunoglobulin G (IgG) may be used for identifying underlying malignancies.• A scheme of screening of cancers frequently reported in the setting of glomerular disease is important.
Journal Title: Translational Oncology
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!