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Highlights • Culture DCs with GM-CSF + IL-4 + IL-15 (IL-15 DCs) can be shortened for 6 days.• IL-15 DCs showed high expression levels of costimulatory receptors, IFN-γ and IL-12p70.•… Click to show full abstract
Highlights • Culture DCs with GM-CSF + IL-4 + IL-15 (IL-15 DCs) can be shortened for 6 days.• IL-15 DCs showed high expression levels of costimulatory receptors, IFN-γ and IL-12p70.• IL-15 DCs showed strong stimulation toward T, CIK and NK cells.• The activated lymphocytes showed high cytotoxicity against myeloma cells.
Keywords:
myeloma;
dcs;
dendritic cells;
potent immunomodulatory;
cells potent;
novel dendritic
Journal Title: Translational Oncology
Year Published: 2022
Link to full text (if available)
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Journal Title: Translational Oncology
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!