LAUSR

Solid graft recipients are at an increased risk of serious complications and death. Out of 130 outpatient recipients of pancreas grafts at our Clinic, 20 (15.73%) had a confirmed SARS-CoV-2 infection. Each patient had a different course of the disease and the forms of infection varied from mild to severe and lethal. According to recommendations, after confirmation of the infection mycophenolate mofetil (MMF) was withdrawn and the immunosuppression was based on steroids and a calcineurin inhibitor. In this study, we performed an analysis of the course of Covid-19 infection in patients after pancreatic transplantation. 20 pancreas recipients were confirmed covid 19 infection. 4 required hospitalization due to severe complications. Patients reported weakness, excessive intensity fatigue, shortness of breath with exertion, cough, periodically increased temperature. Weakness and fatigue persisted in these patients for about 6 weeks. In 2 cases there was a need for oxygen supplementation and empirical antibiotic. Mortality was 5% and there was one graftectomy. In no other cases, deterioration of pancreas graft, as well as kidney graft, was observed. The course of SARS-CoV-2 infection in solid graft recipients is similar to the rest of the population. Because of immunosuppression, recipients are used to avoidance of the crowds and accustomed to mask obligation.