Determining lymph node metastases in dogs with neoplasia is important in staging and developing a therapeutic plan. In this study, the clinical efficacy of combined lymphosonography and strain elastography was… Click to show full abstract
Determining lymph node metastases in dogs with neoplasia is important in staging and developing a therapeutic plan. In this study, the clinical efficacy of combined lymphosonography and strain elastography was evaluated for its ability to identify metastatic mandibular lymph nodes. Data from clinically healthy dogs (n = 16) and those with head/neck tumors (n = 11) were enrolled. Strain elastographic patterns were classified according to the percentage of the stiffness lymph node area (grade 1-4/4). Lymphosonographic images were evaluated quantitatively (visualization of lymphatic vessels/lymph nodes; contrast transit time) and qualitatively (enhancement pattern). There was a significant difference in the strain elastographic pattern (P = 0.011) and lymphosonographic contrast enhancement (P = 0.001) in the metastatic nodes compared to clinical healthy or non-metastatic nodes. Mandibular lymph nodes with filling defects after lymphosonography and high-grade strain elastographic patterns suggested metastasis, and the combination of lymphosonography and strain elastography was useful for identifying malignancy.
               
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