LAUSR

We read with great interest the article by Kapoor et al, “Evolving Strategies in the Treatment of Tuberous Sclerosis Complex-associated Angiomyolipomas (TSCAML),” providing valuable information on localized and systemic therapy in the management of TSC-AML. However, there was a numeric error in the context. Updated criteria from the 2012 International Tuberous Sclerosis Complex Consensus Conference specify 11 major and 6 minor disease features, instead of 9 minor disease features, used to establish a clinical TSC diagnosis. In addition, current guidelines consider the presence of 2 major features sufficient for a definite TSC diagnosis; however, we should notice that a combination of the 2 major clinical features (lymphangioleiomyomatosis and angiomyolipomas) without other features does not meet criteria for a definite diagnosis.