LAUSR

Seminoma is a very common germ cell tumor (GCT) of the testicle. It is a malignant neoplasm and is one of the most treatable and curable cancers, with a survival rate of over 95% if discovered in early stages. Primary extragonadal GCTSs (EGCTs) are rare, and nearly two thirds are seminomatous tumors. As majority of the EGCTs originate from the midline structures, commonly reported locations include the mediastinum, thymus, retroperitoneal organs, and pineal gland. EGCTs have a good prognosis and a low rate of metastatic potential. They are different from primary GCTs with respect to distribution of histological subtypes, delayed presentation of EGCT, and nonseminomatous tumors are often associated with Klinefelter syndrome and hematological malignancies. In the absence of primary testicular involvement, seminoma originating from the prostate is extremely rare. Our extensive research yielded only 6 reported cases from all around the world. We describe the case of a middle-aged male who presented with lower urinary tract symptoms suggestive of benign prostatic obstruction. Prostate-specific antigen (PSA) was normal and his symptoms remained unresponsive to alpha-blockers. However, histopathology confirmed the prostate as the primary location of seminoma following extensive imaging workup. Four cycles of Bleomycin, Etoposide, and Platinum chemotherapy were given postoperatively, and complete response was obtained.