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Rotavirus vaccine effectiveness in low-income settings: An evaluation of the test-negative design

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Highlights • Rotavirus vaccines (RVs) have been recently introduced in low-income settings.• Accurate post-introduction monitoring of RV effectiveness is important.• The test-negative design (TND) is used to measure RV effectiveness.•… Click to show full abstract

Highlights • Rotavirus vaccines (RVs) have been recently introduced in low-income settings.• Accurate post-introduction monitoring of RV effectiveness is important.• The test-negative design (TND) is used to measure RV effectiveness.• The TND was evaluated using randomized trials of RV in sub-Saharan Africa and Asia.• The TND is an appropriate method to measure RV effectiveness in low-income settings.

Keywords: test negative; negative design; income settings; low income; effectiveness

Journal Title: Vaccine
Year Published: 2017

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