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Highlights • Antigenicity of rT-N. meningitidis-MIP vaccine batches is reproducible in mice.• Antibodies to rT-Nm-MIP cross-react with surface Ng-MIP and adhere to gonococci.• Antisera to rT-Nm-MIP are cross-bactericidal for gonococci.•… Click to show full abstract
Highlights • Antigenicity of rT-N. meningitidis-MIP vaccine batches is reproducible in mice.• Antibodies to rT-Nm-MIP cross-react with surface Ng-MIP and adhere to gonococci.• Antisera to rT-Nm-MIP are cross-bactericidal for gonococci.• Meningococcal OM can be engineered to express T-Nm-MIP.
Keywords:
recombinant truncated;
bactericidal;
truncated neisseria;
neisseria meningitidis;
immunization recombinant;
mip
Journal Title: Vaccine
Year Published: 2018
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Journal Title: Vaccine
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!