"The role of immune correlates of protection on the pathway to licensure, policy decision and use of group B Streptococcus vaccines for maternal immunization: considerations from World Health Organization consultations"

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The role of immune correlates of protection on the pathway to licensure, policy decision and use of group B Streptococcus vaccines for maternal immunization: considerations from World Health Organization consultations

Highlights • There is a major public health need for GBS vaccines for maternal immunization.• Important obstacles lie in the way of a pivotal clinical efficacy trial for licensure.• A vaccine development pathway based on an immune correlate of protection is envisaged.• Key considerations and priority activities for success are presented, based on WHO consultations.

Keywords: protection; vaccines maternal; maternal immunization; health; licensure

Journal Title: Vaccine
Year Published: 2019

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