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Humoral and cellular immune response induced by rVSVΔG-ZEBOV-GP vaccine among frontline workers during the 2013–2016 West Africa Ebola outbreak in Guinea

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Highlights • We found rVSVΔG-ZEBOV-GP to be immunogenic at 28- and 180-days post vaccination.• At 28 days post-vaccination, seroresponse rate was higher in the high-risk group.• There is a significant… Click to show full abstract

Highlights • We found rVSVΔG-ZEBOV-GP to be immunogenic at 28- and 180-days post vaccination.• At 28 days post-vaccination, seroresponse rate was higher in the high-risk group.• There is a significant pairwise correlation at 28 days post-vaccination between assays.• One dose of rVSVΔG-ZEBOV-GP induces a cellular response that increased with time.

Keywords: response; rvsv zebov; days post; post vaccination; zebov; vaccine

Journal Title: Vaccine
Year Published: 2020

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