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Evaluation of pneumococcal meningitis clusters in Burkina Faso and implications for potential reactive vaccination

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Highlights • From 2011 to 2017, Burkina Faso had 20 pneumococcal meningitis clusters of ≥ 5 cases per district/week.• Clusters had a maximum weekly incidence of 7 cases and a… Click to show full abstract

Highlights • From 2011 to 2017, Burkina Faso had 20 pneumococcal meningitis clusters of ≥ 5 cases per district/week.• Clusters had a maximum weekly incidence of 7 cases and a maximum duration of 4 weeks.• Most clusters occurred prior to 13-valent pneumococcal conjugate vaccine introduction.• Clusters were caused by a mixture of serotypes, with serotype 1 being most common.• Due to the limited cluster size and duration, there were no clear indications for reactive vaccination.

Keywords: pneumococcal meningitis; burkina faso; reactive vaccination; meningitis clusters

Journal Title: Vaccine
Year Published: 2020

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