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A very simple model to account for the rapid rise of the alpha variant of SARS-CoV-2 in several countries and the world

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Since its first detection in the UK in September 2020, a highly contagious version of the coronavirus, the alpha or British variant a.k.a. B.1.1.7 SARS-CoV-2 virus lineage, rapidly spread across… Click to show full abstract

Since its first detection in the UK in September 2020, a highly contagious version of the coronavirus, the alpha or British variant a.k.a. B.1.1.7 SARS-CoV-2 virus lineage, rapidly spread across several countries and became the dominant strain in the outbreak. Here it is shown that a very simple evolutionary model can fit the observed change in frequency of B.1.1.7 for several countries, regions of countries and the whole world with a single parameter, its relative fitness f, which is almost universal f ≈ 1.5. This is consistent with a 50% higher transmissibility than the local wild type and with the fact that the period in which this variant takes over has been in all the studied cases around 22 weeks.

Keywords: variant sars; several countries; world; sars cov; simple model

Journal Title: Virus Research
Year Published: 2021

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