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Multifocal Infra-Tentorial Pilocytic Astrocytoma in an Adult Patient: A Case Report.

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BACKGROUND Pilocytic astrocytoma (PA) is a benign glial tumour typically presenting in children. It is rare for adults to present with PA and even less likely to manifest with multiple… Click to show full abstract

BACKGROUND Pilocytic astrocytoma (PA) is a benign glial tumour typically presenting in children. It is rare for adults to present with PA and even less likely to manifest with multiple foci of lesions especially in non-optic or hypothalamic locations. CASE DESCRIPTION Our patient was a 37-year old gentleman presenting with varied cranial neuropathies, cerebellar dysfunction and long tract signs with imaging demonstrating three discrete ill-defined contrast-enhancing lesions affecting the cerebellar peduncles, brainstem and cervico-medullary junction. Neuro-navigation guided biopsy confirmed WHO Grade 1 PA that was treated with radiotherapy. CONCLUSIONS To our knowledge, we believe this is the first case with multifocal infra-tentorial PA on presentation in an adult patient in the absence of a prior history of associated risk factors such as neurofibromatosis 1 (NF1) or chemo-radio-therapeutic intervention.

Keywords: adult patient; pilocytic astrocytoma; infra tentorial; case; multifocal infra

Journal Title: World neurosurgery
Year Published: 2019

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