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Repair of Cranial Bone Defects in Children Using Synthetic Hydroxyapatite Cranioplasty (Custombone®).

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INTRODUCTION In pediatric cases, the use of autologous bone tissue to repair cranial bone defects is often impossible. The synthetic hydroxyapatite bone substitute (CUSTOMBONE®) can be a good alternative especially… Click to show full abstract

INTRODUCTION In pediatric cases, the use of autologous bone tissue to repair cranial bone defects is often impossible. The synthetic hydroxyapatite bone substitute (CUSTOMBONE®) can be a good alternative especially in case of a large bone defect that has to be repaired. MATERIALS AND METHODS The present study focuses on a pediatric series of 30 children who underwent cranioplasty with a CUSTOMBONE® implant. Patient age ranged from 8 months to 16 years, with a mean age of 7 years and 8 months. The most common indication for cranioplasty was post-traumatic decompressive craniectomy. RESULTS No complications were reported. Cosmetic results were satisfactory in every patient. Only one implant had to be changed after a severe head trauma due to an epileptic seizure in the early postoperative period. In all patients, cerebral blood flow improved during the postoperative phase. Complete implant osteointegration is a long process as mean time to begin was 13 months (range: 3-22 months). Mean patient follow-up was 6,7 years. DISCUSSION Successful prosthesis integration depends on the accuracy of the preoperative model. The minimum thickness of the implant (4 mm) represent a challenge in very young children but we used it with success in this series. Moreover, high costs represent another limitation for its use. CONCLUSION In our opinion, the CUSTOMBONE® implant meets all necessary conditions for good clinical outcome: excellent protective properties, restoration of normal intracranial physiology, satisfactory cosmetic results, a good integration in the autologous bone and a good resistance in case of trauma.

Keywords: custombone; synthetic hydroxyapatite; bone; cranial bone; bone defects; repair cranial

Journal Title: World neurosurgery
Year Published: 2019

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