LAUSR

Objective The clinical prognostic value of the Spinal Instability Neoplastic Score (SINS), in the context of vertebrectomy for neoplasia, has not yet been established. This retrospective study of 134 patients aims to evaluate the efficacy of the SINS to predict outcomes and survival after vertebrectomy for malignancy. Methods The patients were classified into 2 groups: indeterminate stability (SINS 7–12) and unstable (SINS 13–18). Outcomes assessed included survival days after procedure, neurological function (modified Frankel grade), operative time, blood loss, complications, construct failure, and length of inpatient stay. Results The indeterminate group included 68 patients, whereas the unstable group included 66 patients. No patients were classified as stable (SINS 0–6). The median survival was 225 days (interquartile range, 81–522 days). There was a statistically significant difference (P Conclusions This study demonstrates a statistically significant increased survival in the indeterminate cohort. These results demonstrate the potential ability of the SINS to act as a clinical prognostic tool with regard to survival time.