LAUSR

OBJECTIVE We performed a fine white fiber dissection to demonstrate the extensive connections of the corpus callosum. MATERIAL AND METHODS Three formalin fixed frozen cadaveric human brain specimens were dissected using Klingler's technique. On one half of each hemisphere the superior connections of the corpus callosum were dissected and in the other half the inferior connections of the corpus callosum were dissected. RESULTS The mean length of the corpus callosum from the rostrum to the splenium was 7.8 cm. The fibers of the corpus callosum were classified as superior/dorsal radiations, inferior/ventral radiations, anterior radiations and posterior radiations. The entire transverse length of the dorsal callosal radiation from one hemisphere to the other was 8.1 cm. For anterior interhemipheric approaches a lesion in the anterior part of the body not extending beyond 3.5 cm from the genu was found to be safe with regards to crossing motor fibers. CONCLUSION The corpus callosum was found to have intricate connections with all the lobes of the cerebral hemispheres including the insular region and the limbic and paralimbic areas. Based on the course and traverse of the callosal fibers a transverse incision in the corpus callosum can be preferred when performing a callosotomy to access intraventricular lesions as this splits the callosal fibers instead of transecting them. The analysis of course of the callosal radiations enhances understanding of the growth pattern of primary corpus callosal gliomas and to design a safe surgical strategy.