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Protective Efficacy of Candidate Vaccines Prior to Human Clinical Trials.

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Immunization of animals is one of the key standards for evaluation of vaccine efficacy prior to human clinical trials. However, vaccine organizations should not over-interpret these results as protective efficacy… Click to show full abstract

Immunization of animals is one of the key standards for evaluation of vaccine efficacy prior to human clinical trials. However, vaccine organizations should not over-interpret these results as protective efficacy in animals may not be relevant in humans. Screening of vaccine candidates has recently been performed by several in vitro human models. A properly designed in vitro approach opens new venues for vaccine development.

Keywords: prior human; efficacy candidate; human clinical; protective efficacy; efficacy; clinical trials

Journal Title: Journal of pharmaceutical sciences
Year Published: 2018

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